A blood test for Alzheimer's??? Not so fast....

Thursday, March 13, 2014 - 12:22pm

Nature Medicine published a study reporting how in a cohort of 500 someodd adults -- average age in their 70's -- a blood measure of various lipids predicted the group who, over three yeas of follow up, was likely to develop either mild cognitive impairment or Alzheimers' disease dementia. I spoke with...

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Medicine by the numbers

Sunday, February 16, 2014 - 2:19pm

Follow this link to my NY Times op-ed on the new American College of Cardiology guidelines on the treatment of cardiovascular disease. I write how the guidelines that feature an "omnibus risk calculator" -- that name! -- are yet another example of the rise of actuarial practices in medicine, what I have coined "...

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How learning your genetic risk can transform you....

Sunday, February 16, 2014 - 2:12pm

The American Journal of Psychiatry reports two remarkable findings: After cognitively normal older adults learns they have the ε4 allele of the APOE gene that increases risk of developing Alzheimer’s disease dementia, they perform worse...

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My Top 10 Books…

Sunday, December 29, 2013 - 1:00am

Order nonspecific, this is my list. Each one has been a close friend with whom I’ve talked to and listened to and, after in some cases, after years apart, looked up and gotten back in touch with.

Middlesex by Jeffrey Eugenides

Sentimental Education by Gustave Flaubert

Lolita by Vladimir Nabakov

Blood Meridian by Cormac McCarthy

The Heart of the Matter by Graeme Greene

Let the Great World Spin by Colum McCann

Prescribing by...

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Been thinking about how we think about agitation in persons with dementia and how, as a result, we treat it, or really fail to treat it....

Friday, November 29, 2013 - 7:34pm

.... because we think of it as just a brain disease.

Yeats’ “Quarrel in Old Age” explains what I’m thinking. First stanza: imagine the speaker; a daughter, just off the phone following a call from the nursing home staff who care for her mother, and, in the second stanza, pay close attention to the punctuation.

“Where had her sweetness gone?
What fanatics invent
In this blind bitter town,
Fantasy or incident
Not worth thinking of...

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A diary of The Tragic Obsession Tour

Thursday, November 14, 2013 - 6:45am

Keeping a diary of the Tour... Reads not like a blog but a book with the oldest entry first (a "golb" perhaps?), so to read the latest diary entry, you'll have to click on "learn more" and scroll all-the-way-down....

October 11th -- Two big New York City events kicked off the tour: the New School's Fiction Forum on October 10th and the New York Academy of Medicine on October 11th.

Vigorous discussions of why write a novel instead of a biography or essay --...

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